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FRCPath Haem Part 1 EMQs-Transfusion 514

amirhayat2527
5 minutes ago
2 min read

Each option may be used once, more than once, or not at all.

Options

Option

Red cell ABO group

A

Group A

B

Group B

C

Group AB

D

Group O

Question 1 – Scenario 1

A 42-year-old man with acute myeloid leukaemia undergoes an allogeneic haematopoietic stem cell transplant from an unrelated donor.

  • Recipient ABO group: A positive

  • Donor ABO group: O positive

  • The patient is currently on day +5 post-transplant and has not yet achieved neutrophil engraftment.

  • He develops symptomatic anaemia with a haemoglobin of 68 g/L and requires red cell transfusion.

Which ABO group of red cells is most appropriate?


Question 2 – Scenario 2

A 35-year-old woman with aplastic anaemia undergoes an allogeneic HSCT from her HLA-matched sibling.

  • Recipient ABO group: B positive

  • Donor ABO group: O positive

  • She is currently on day +8 post-transplant, before engraftment.

  • She develops symptomatic anaemia requiring red cell support.

Which ABO group of red cells is most appropriate?


Question 3 – Scenario 3

A 56-year-old man with myelodysplastic syndrome undergoes an allogeneic HSCT.

  • Recipient ABO group: A positive

  • Donor ABO group: AB positive

  • He is currently on day +4 post-transplant, before engraftment, and requires red cell transfusion.

Which ABO group of red cells is most appropriate?


Question 4 – Scenario 4

A 48-year-old woman with acute myeloid leukaemia receives an allogeneic HSCT from an unrelated donor.

  • Recipient ABO group: O positive

  • Donor ABO group: AB positive

  • She is currently on day +7 post-transplant, before engraftment, and requires red cell transfusion.

Which ABO group of red cells is most appropriate?


Question 5 – Scenario 5

A 29-year-old man with acute lymphoblastic leukaemia undergoes an allogeneic HSCT from an HLA-matched sibling.

  • Recipient ABO group: B positive

  • Donor ABO group: A positive

  • He is currently on day +6 post-transplant, before engraftment, and requires red cell transfusion.

Which ABO group of red cells is most appropriate?


 
 
 

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