FRCPath Haem Part 1 MCQ-Gen Haem 175

A 20yr-old pt with HbSS is on hydroxycarbamide 500 mg BD. Bloods: Hb 90, WCC 2.5, N 1.2 and Plt 60. What is the most appropriate next step?

• Continue current dose and recheck counts in 2 weeks
• Increase hydroxycarbamide dose by 5 mg/kg/day
• Stop hydroxycarbamide and repeat FBC weekly until counts rec
• Add folic acid and continue same dose

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