FRCPath Haem Part 1 MCQ-Gen Haem 196

A 10yr-old PT of Thai origin has moderate anemia, microcytosis, and splenomegaly. HPLC: HbA: 0% HbE: 60% HbF: 39%, HBA2 1%. What is the most likely diagnosis

• HbE trait
• Homozygous HbE
• HbE/β⁰-thalassemia
• HbE/β⁺-thalassemia

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