FRCPath Haem Part 1 MCQ-Haemostasis 320

A 68yr-old pt develops postoperative bleeding. PT and APTT are both prolonged and do not correct on mixing. Factor V activity: <5%. Likely underlying mechanism?

• Congenital factor V deficiency
• Lupus anticoagulant
• Autoantibody against human factor V
• Heteroantibody directed against bovine thrombin

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