FRCPath Haem Part 1 MCQ-Transfusion 136

In a patient on daratumumab whose antibody screen now shows pan-reactivity, which technique is widely used and recommended to allow alloantibody identification?

• Treat patient plasma with 0.2 M DTT
• Treat reagent RBCs with 0.2 M DTT
• Increase incubation temperature to 42 °C
• Use enzyme-treated RBCs only

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