FRCPath Haem Part 1 MCQs - General Haem 456

A 4-year-old boy with HbSS sickle cell disease attends the paediatric haematology clinic for his routine annual review.

He has been clinically well over the past year with no history of stroke or transient neurological symptoms. His vaccinations are up to date, and he is receiving hydroxycarbamide.

On examination, there are no focal neurological deficits.

The consultant discusses screening for cerebrovascular disease and arranges a Transcranial Doppler (TCD) ultrasound to assess his risk of stroke.

According to current recommendations, which age group should routinely undergo TCD screening for stroke risk in children with sickle cell disease?

A. 1–15 years

B. 2–16 years

C. 3–18 years

D. 5–16 years

E. 2–18 years