FRCPath Haem Part 1 MCQ- Gen Haematology 109

A 24yr-old man presents with acute haemolysis 2 weeks after infection. DAT: C3d only. Serum studies show polyclonal IgM with cold agg titre 1:128. Management?

• Rituximab Therapy
• High-dose corticosteroids
• Supportive care
• Plasmapheresis to remove IgM

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