FRCPath Haem Part 1 MCQ-General Haematology 53
- amirhayat2527
- Sep 5
- 0 min read
A 25yr-old man presents with mild anaemia. MCHC of 36 g/dL, reticulocytosis, and negative DAT. EMA binding test is decreased. Which mutation is responsible?
PKLR
SPTA1
ANK1
ALAS1
Correct answer: ANK1, majority of cases of HS has this mutation