FRCPath Haem Part 1 MCQ-Oncology 82

A newly diagnosed APML patient is about to start ATRA + ATO. Baseline WBC: 18 × 10⁹/L. What is the best preventive strategy for differentiation syndrome?

• Withhold ATRA until day 14
• Delay ATRA until WBC <10 × 10⁹/L
• Prescribe Hydroxycarbamide
• Reduced Dose ATRA

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