FRCPath Haem Part 1 MCQ-Transfusion 244

A 50yr-old pt develops jaundice and drop in Hb on day +10 after an allogenic stem cell transplant from O-pos donor to A-pos recipient. Likely Mechanism?

• Donor antibodies against recipient HLA antigens
• Recipient antibodies against donor erythroid precursors
• Donor lymphocytes producing antibodies against recipient RBC
• Recipient plasma reacting with donor lymphocytes

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