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FRCPath Haem Part 1 MCQ-Gen Haem 241

An unwell 3yr-old Burkitt Lymphoma pt with a suspected TLS presents with rapidly rising uric acid and potassium. G6PD status is unknown. What is best action?

  • Wait for G6PD result before giving rasburicase

  • Start allopurinol instead of rasburicase

  • Give rasburicase urgently if clinically necessary

  • Avoid urate-lowering therapy

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