FRCPath Haem Part 1 MCQ-Gen Haem 242

A Patient with Lymphoma was on TLS prophylaxis with Allopurinol. He has developed TLS and started on rasburicase. What should happen to allopurinol?

• Continue alongside rasburicase
• Double the dose of allopurinol
• Half the dose of allopurinol
• Restart Allopurinol 24 h after last rasburicase dose

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